The Advair Diskus 250/50 is a combination of fluticasone propionate and salmeterol xinafoate and is used to treat asthma in the form of powder inhalation.

Advair Diskus usage

Usage of the device will vary depending on age, but not gender with adult and child options:


Allow approximately 12 hours between doses – ideally once upon waking up and again in the evening – 12 hours after.

For ≥12 years: Initially, one inhalation of 100/50 or 250/50 or 500/50 twice daily, based on disease severity and any applicable previous asthma therapy. If an insufficient response after two weeks of treatment, use the next higher strength of the maximum of 1 inhalation of the Advair Diskus 500/50 twice daily, 12 hours apart.


For <4 years: Has not yet been established, seek the help of a doctor for specialist advice.

For <12 years: Allow approximately 12hrs between doses. Asthma: 4–11yrs: 1 inh of 100/50 twice daily. Rinse mouth after use.

Advair Diskus contraindications

Contraindications of the Advair Diskus are as follows:

  • Primary treatment of status asthmaticus or other acute episodes of asthma or COPD requiring intensive measures.
  • Severe milk protein hypersensitivity.

How many puffs in the Advair Diskus?

There is a lack of literature on the number of ‘puffs’ in the Advair Diskus, however with the guidelines present that each of the Advair Diskus inhalers of each of the ranges should be used and changed within one month, after the moisture-protective foil pouch is removed, to avoid expiry issues.

With a dosage of 1x inhalation a maximum of twice per day for a single month at 12 hours apart – it can be safe to assume that the Advair Diskus has a maximum lifespan of approximately 70 ‘puffs’ before it should be replaced.

Advair Diskus 250/50 Walmart price

The Advair Diskus 250/50 is priced currently at Walmart for $287.81 for a single inhaler. Please note this is the list price and without the consideration of any coupons, offers or savings at the time of purchase.

Advair Diskus 250/50 coupon

To combat the costs of the Advair Diskus 250/50, you may be entitled to a coupon as described on their website. Savings can be as much as $50 direct from the manufacturer, but of course, other options of coupons do exist.

Sites such as ‘groupon’ and will always have potential coupons available to make sure that everyone can afford the treatment that they require.

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